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B-Vitamins (B3, B5, B6, B12)

Coenzyme support for cellular energy metabolism

Science and Ingredients — Formulation Research

This entry documents the biological mechanisms, human research, and formulation rationale for ingredients used in Steady Energy. Content is provided for transparency and educational purposes, not marketing.


Red cherries on rustic wooden surface, green leaves in background, vibrant and fresh.
Diagram illustrating the citric acid cycle with a focus on coenzymes, highlighting the role of B vitamins in forming key coenzymes like NADH, FADH2, and others essential for cellular metabolism.

Category


Enzymatic energy production and nervous system support


Why it's included


To support enzymatic processes involved in energy metabolism, neurotransmitter synthesis, and normal nervous system function during sustained physical and mental demand.



What it is


B-vitamins are a group of water-soluble micronutrients that function primarily as coenzymes in metabolic reactions. Unlike stimulants, B-vitamins do not provide energy directly, but are required for the biochemical processes that convert carbohydrates, fats, and proteins into usable cellular energy.


Steady Energy includes selected B-vitamins that are directly involved in energy metabolism and nervous system function.



Mechanism of action


Coenzyme function


B-vitamins act as cofactors for enzymes involved in:


  • Glycolysis and the citric acid cycle


  • Fatty acid oxidation


  • Amino acid metabolism


  • Mitochondrial ATP production


Without adequate B-vitamin availability, these pathways become less efficient.


Nervous system support


Several B-vitamins play essential roles in neurotransmitter synthesis and nerve signaling, supporting cognitive function and neuromuscular coordination during prolonged workload.


These roles are foundational and permissive, not stimulatory.



Included B-vitamins in Steady Energy


Vitamin B3 (Niacin)

Supports redox reactions central to energy metabolism through NAD⁺/NADH pathways.


Vitamin B5 (Pantothenic Acid)

Required for synthesis of coenzyme A, which is essential for fatty acid metabolism and the citric acid cycle.


Vitamin B6 (Pyridoxine)

Involved in amino acid metabolism and neurotransmitter synthesis.


Vitamin B12 (Cobalamin)

Supports red blood cell formation, nervous system function, and methylation pathways.



Evidence overview


  • B-vitamins are essential cofactors in human energy metabolism


  • Deficiency impairs cellular energy production and nervous system function


  • Supplementation supports normal metabolic processes where intake is inadequate


  • Effects are foundational rather than acutely perceptible



Why this matters for long workdays


Sustained physical and mental work increases metabolic demand. Even marginal inadequacy of key micronutrients can reduce metabolic efficiency over time, contributing to fatigue and reduced performance.


Supporting coenzyme availability helps ensure energy-producing pathways function as intended across extended shifts.



Role in Steady Energy


B-vitamins are included to support the biochemical infrastructure that underlies energy production and nervous system function. They complement ingredients that influence hydration, stimulation, stress adaptation, and mitochondrial activity.


This reinforces Steady Energy’s design as a system, not a single-mechanism product.



References


Human physiology and peer-reviewed research are cited where available.


  1. Kennedy DO. B vitamins and the brain: mechanisms, dose and efficacy — a review. Nutrients, 2016.

    https://pubmed.ncbi.nlm.nih.gov/?term=Kennedy+DO+B+vitamins+brain+mechanisms


  2. Depeint F et al. Mitochondrial function and micronutrients. Journal of Clinical Pathology, 2006.

    https://pubmed.ncbi.nlm.nih.gov/?term=Depeint+mitochondrial+function+micronutrients


  3. Stover PJ. Vitamin B12 and older adults. Current Opinion in Clinical Nutrition and Metabolic Care, 2010.

    https://pubmed.ncbi.nlm.nih.gov/?term=Stover+vitamin+B12+metabolism


  4. Ames BN. Micronutrients prevent mitochondrial decay and cognitive decline. FASEB Journal, 2006.

    https://pubmed.ncbi.nlm.nih.gov/?term=Ames+micronutrients+mitochondrial+decay



This ingredient profile is part of the Steady Energy formulation research series.


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